The Gallery has been in operation since 1988 and includes about 250 works by the most important 19th and 20th-century Greek artists, such as Ghyzis, Volanakis, Iakovides, Parthenis, Maleas, Vyzantios, Moralis, Malamos, Prekas, Tetsis and others.

Both the Gallery's collection and the modern three-storeyed building in which it is housed, were donated to the Evangelos Averoff-Tossizza Foundation by its creator and founder E. Averoff.

The Averoff Gallery's collection is considered by specialists to be one of those which cover this particular period most completely.

Some of the most important exhibits of the museum are:

P. Prossalendis the younger, "Portrait of G. Averoff".

Nikiphoros Lytras, "The blowing up of the Turkish flagship by Kanaris", 143x109 cm.

C. Parthenis, "G. M. Averoff", 85x68 cm.