The Archaeological Museum of Arta is located at the southern edge of the modern city, next to the eastern bank of the River of Arachthos, a short distance from the historic Bridge. It opened its doors to the public in 2009 and in 2024, following a comprehensive upgrade of its infrastructure and services to the public, it was recognized as a certified museum by the Hellenic Ministry of Culture.

It is dedicated exclusively to Ambracia, the colony founded by the Corinthians in the last quarter of 7th c. BC on the northern slopes of the hill of Peranthi, near the once navigable river, and nowadays extends under the modern city. Ambracia emerged and remained, throughout almost its entire history, the urban, political, economic and artistic center of ancient Epirus.

Through numerous findings covering a long period from Archaic to Roman times, the Museum's exhibition presents life in the ancient city through three main thematic units dedicated to public life, cemeteries, and houses and daily private life of the Ambracians. Two small sections, at the beginning and end of the exhibition, serve as an introduction and epilogue, respectively, to the museum's narrative.