At the northernmost edge of the eastern coast of Crete lie the ruins of a settlement which flourished during the Late Minoan period (1550-1220 B.C.). At the same site, however, are preserved remains of the Early and Middle Minoan periods (3000-1550 B.C.), mostly cemeteries with well-built ossuaries, and ruins of spacious houses. The site ceased to be inhabited at the same time when Zakros was abandoned (1450 B.C.) but was reoccupied during the Late Minoan III period (1300-1200 B.C.). The city covered a total area of more than 50,000 sq.m., was densely inhabited but not fortified.

To the NE of one of the city's sectors lies the sanctuary of Diktaian Zeus, which belonged administratively to the city of Itanos. Cult practice was continuous from the Geometric period (8th century B.C.) until the Roman conquest. It seems that the sanctuary was plundered and destroyed by fanatic Christians at the end of the 4th century A.D.